Streptogramin A and B

My Sketchy Pharm Add-on

I know, I know, I should be studying instead of making my own Sketchy pictures, but I needed an excuse to procrastinate yesterday. It was a lot of fun to make, and is far (far) from perfect, but it’s got the few tidbits that our professor wanted us to know about Streptogramin, so I’ve included my class notes and the little picture.**

Side note:
“CLEan TAg” is a phenomenal little mnemonic that I found in the “Clinical Microbiology Made Ridiculously Simple” textbook that I love (link to Amazon here if you like to buy physical books*). It helps you remember which subunit of the ribosome is inhibited by which anti-ribosomal agent:

Where 50S:
C = clindamycin and chloramphenicol
L = linezolid
E = erythromycin (macrolide)
30S:
T = tetracycline and tigeclycine
Ag = aminoglycosides

To include streptogramins, which inhibits the 50S as well, I changed “CLEan TAg” to “CLEanS TAg,” which is what you see below.

And now onto the Sketchy Addendum:

Ceremonial Delfin Killing in the Pristine Kingdom of Queen Melsby

Note: Streptogramin has a NARROW spectrum, targeting most Gram positive microbes. It treats MRSA (no mercy) but also VRE (I just didn’t have a way to incorporate it).
I hope it helps somewhat! Had a lot of fun making it, might even fix it up in the future. If you found an error, please let me know!

** When I looked these up on Wikipedia, it states that both dalfo- and quinu-pristine are derived from Streptogramin A, which is sadly not what we were told in class. So now I’m not sure where the truth lies…

*Regarding Clinical Micro Made Ridiculously Simple: I bought the textbook and really like it, but it’s sometimes tough to use it because I run out of time after watching Sketchy. I used it mostly for antibiotics during micro and even pharma. If you’d like to buy it, the link I attached is an affiliate link, which means I get a small percentage from Amazon, at no extra cost to you. If you prefer to buy used book (which I often do, except in this case), ask upperclassmen at your university! Happy studying.